What to Expect

An effective, less disruptive treatment option

The Radixact® System with the TomoTherapy technology maximizes radiation delivered to the target — while helping to minimize radiation dose to surrounding healthy tissues. The result is highly personalized treatment designed to significantly reduce the risk of the side effects that too often disrupt the lives of patients during and after treatment. Clinical studies support the use of the TomoTherapy technology in the treatment of prostate cancers and show evidence of excellent tumor control with minimal radiation delivered to surrounding healthy tissues.1, 2, 3, 4, 5, 6


Radixact treatment is an outpatient procedure that does not require incisions or general anesthesia. Most patients will not require hospitalization a long recovery period. Radixact treatment also eliminates the inconvenience and risk associated with radioactive seed implants.


Conventional radiation therapy typically requires patients to have treatment 5 days a week for 8 weeks. Clinicians using the Radixact System may choose to reduce this course of treatment due to the precise nature of delivery, significantly reducing the time you spend undergoing radiation treatments


The Radixact System was designed to deliver precise and accurate radiation dose to the target which can help significantly reduce the risk of side effects such as sexual, urinary or bowel function.

A faster return to everyday life

With Radixact treatment, most patients can continue normal activity during and immediately following treatment — compared to the typical requirements to limit normal activity for several weeks with traditional surgery. Just as importantly, the Radixact System reduces the risk of common side effects, protecting quality of life both during and after treatment. In some circumstances, side effects may occur.

Your Radixact treatment process


The Radixact System treatment process begins with a consultation with a radiation oncologist who will provide perspective on this as a treatment option specific to your condition. The physician will review your biopsy results, imaging and other medical conditions.


Radixact treatment for prostate cancers involves a multi-disciplinary team approach, which may include several specialists:

  • Medical Oncologist
  • Urologist
  • Radiation Oncologist
  • Medical Physcist
  • Radiation Therapist
  • Medical Support Staff


Some tumors may require the placement of fiducials within the prostate. Fiducials are markers that show on x-ray to help the Radixact System pinpoint the tumor’s exact location. They are implanted in a short, minimally invasive outpatient procedure prior to treatment planning.


Prior to Radixact treatment, you will undergo imaging scans so that your treatment team can determine the exact size, shape and location of your prostate tumor, as well as nearby anatomy.


Following this preparatory visit, you could return for specific imaging for radiation therapy treatment planning. Using CT, MRI and/or PET scan data, your treatment team will determine the area to be targeted by radiation, the radiation dose, and identify critical structures — such as the rectum, bladder – where radiation should be minimized.

The medical physicist will then calculate a precision-optimized radiation delivery plan, leveraging the Radixact System’s sophisticated treatment planning algorithms to help deliver a safe and personalized treatment.


Approximately one to two weeks after your treatment plan is finalized, you will begin treatment sessions. Treatment sessions are non-invasive outpatient procedures, and nothing will be required of you during treatment. No patient restraints. No anesthesia.

On each treatment day, you will be carefully positioned on the treatment couch. The Radixact System acts as both a CT scanner and treatment delivery machine. This unique combination enables doctors to take a CT scan immediately before each treatment. With that image, they can verify the position of the tumor and, if necessary, adjust your position to help make sure radiation is delivered with high precision.

Once the short imaging procedure is complete, treatment delivery will begin. As the Radixact patient couch moves you at a deliberate pace through the center of the gantry, radiation beamlets are delivered precisely to the treatment area from 360 degrees. If the Synchrony® technology* is used to synchronize and adapt the beams to your breathing and tumor motion, you will undergo a short procedure between imaging and treatment delivery to create a breathing model that will help predict your breathing cycle.

You can expect your Radixact treatment to require daily sessions for 6-8 weeks. Because the Radixact System can deliver radiation continuously, without requiring interruptions to reposition, the entire treatment process typically lasts 10-20 minutes — including patient set-up time.

*The Synchrony technology is an optional upgrade available for purchase by hospitals.


Most patients can continue normal activity during and immediately following treatment. Most patients experience minimal side effects and can quickly return to their daily routines with little interruption to their normal activities during or following their treatment.

Your medical team will discuss all possible side effects prior to treatment and may prescribe medication to control any side effects, should they occur. You also should schedule and attend any follow-up appointments.

Find a Radixact Treatment Center

Learn More About Radixact Treatment


1 Di Muzio NG, Fodor A, Noris Chiorda B, et al. “Moderate Hypofractionation with Simultaneous Integrated Boost in Prostate Cancer: Long-term Results of a Phase I-II Study.” Clin Oncol (R Coll Radiol). 2016 Aug;28(8):490-500. doi: 10.1016/j.clon.2016.02.005.

2 Tomita N, Soga N, Ogura Y, et al. “High-dose radiotherapy with helical tomotherapy and long-term androgen deprivation therapy for prostate cancer: 5-year outcomes.” J Cancer Res Clin Oncol. 2016 Jul;142(7):1609-19. doi: 10.1007/s00432-016-2173-9.

3 Yamazaki H, Masui K, Suzuki G, et al. “High-Dose-Rate Brachytherapy Monotherapy versus Image-Guided Intensity-Modulated Radiotherapy with Helical Tomotherapy for Patients with Localized Prostate Cancer.” Cancers (Basel). 2018 Sep 10;10(9). pii: E322. doi: 1.

4 Macias VA, Barrera-Mellado I. “Ultra-hypofractionated radiation therapy for unfavourable intermediate-risk and high-risk prostate cancer is safe and effective: 5-year outcomes of a phase II trial.” BJU Int. 2019 Oct 15. doi: 10.1111/bju.14925.

5 Fodor A, Berardi G, Fiorino C, et al. “Toxicity and efficacy of salvage carbon 11-choline positron emission tomography/computed tomography-guided radiation therapy in patients with lymph node recurrence of prostate cancer.” BJU Int. 2017 Mar;119(3):406-413.

6 Saldi S, Bellavita R, Lancellotta V, et al. “Acute Toxicity Profiles of Hypofractionated Adjuvant and Salvage Radiation Therapy After Radical Prostatectomy: Results of a Prospective Study.” Int J Radiat Oncol Biol Phys. 2019 Jan 1;103(1):105-111. doi: 10.10.

Share Your Story

Educating others about your experience with the Radixact® or TomoTherapy® System can help others who face similar decisions about their own cancer treatment choices.

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Please note: Accuray is the manufacturer of the CyberKnife®, TomoTherapy®, and Radixact® Systems. As the manufacturer, we are unable to provide specific medical advice, view medical records, or schedule appointments.
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Important Safety Statement: Most side effects of radiotherapy, including radiotherapy delivered with Accuray systems, are mild and temporary, often involving fatigue, nausea, and skin irritation. Side effects can be severe, however, leading to pain, alterations in normal body functions (for example, urinary or salivary function), deterioration of quality of life, permanent injury and even death. Side effects can occur during or shortly after radiation treatment or in the months and years following radiation. The nature and severity of side effects depend on many factors, including the size and location of the treated tumor, the treatment technique (for example, the radiation dose), the patient’s general medical condition, to name a few. For more details about the side effects of your radiation therapy, and if treatment with an Accuray product is right for you, ask your doctor.